FAQs

What is neutropenia?

Neutropenia means “low white blood cells”, which help fight infections. During this time, the body is more prone to infections from food and the environment.

Certain foods can carry bacteria. When immunity is low, these bacteria can cause serious infections. A “safe, well-cooked diet” helps reduce this risk.

A neutropenic diet focuses on:
● Freshly cooked food
● Good hygiene
● Avoiding raw or unpasteurised foods
It does not mean tasteless or poor nutrition.

Well-cooked foods
● Freshly cooked rice, chapati, and dal
● Fully cooked vegetables
● Well-cooked chicken, fish, eggs
● Pasteurised milk and curd (boiled milk preferred)
Fruits
● Fruits that can be peeled (banana, orange, apple)
● Wash thoroughly before peeling
Others
● Biscuits, bread (fresh, not mouldy)
● Packaged foods from reliable brands (within expiry)

Raw or undercooked foods
● Raw salads, sprouts
● Sushi, raw eggs
● Half-cooked meat or fish
Unpasteurised products
● Raw milk, street-vendor curd
● Soft cheeses (unless pasteurised)
Outside and street food
● Chaats, pani puri, cut fruits
● Buffets and uncovered food

Yes, but:
● Eat ‘only cooked vegetables’
● Eat ‘peeled fruits only’
● Avoid raw salads and chutneys

Drink ‘boiled and cooled water’ or ‘RO/filtered water’
Avoid water from unknown sources

‘Best avoided during neutropenia’
If unavoidable: * Choose freshly cooked, hot food
* Avoid salads, sauces, ice, and garnishing

● Wash your hands before cooking
● Use clean utensils
● Cook food thoroughly
● Eat food “freshly prepared”
* Avoid storing cooked food for long periods

* Prefer “fresh food”
* If reheating, ensure it is **piping hot**
* Avoid reheating more than once

✔️ Boiled milk
✔️ Pasteurised curd (fresh)
❌ Raw milk
❌ Open, unlabelled dairy products

✔️ Yes, “only fully cooked eggs”
❌ Avoid raw or half-boiled eggs

Follow a neutropenic diet “until your doctor confirms that white blood counts have recovered”

● Eat small, frequent meals
● Choose soft, easy-to-digest foods
● Inform your doctor if appetite loss is severe

Contact your doctor if you have:
● Fever
● Diarrhoea
● Vomiting
● Abdominal pain after eating

What is a high-protein diet?

A high-protein diet includes foods that help:
● Build and repair muscles
● Improve immunity
● Speed up recovery after illness, chemotherapy, or transplant
Protein is especially important during cancer treatment and recovery.

You may need more protein if you:
● are undergoing chemotherapy or a transplant
● Have weight loss or weakness
● Have low immunity or slow healing
● Feel tired most of the time
Protein helps your body heal and stay strong

Most patients need:
● 1–1.5 grams of protein per kg body weight per day
👉 Example:
If weight = 60 kg → protein needed ≈ 60–90 g/day
(Your doctor or dietitian may adjust this)

Vegetarian protein sources
● Dal (toor, moong, masoor)
● Chana, rajma, lobia
● Paneer
● Curd / yogurt
● Milk
● Soybean, tofu
● Peanuts, roasted chana

Non-vegetarian protein sources
● Eggs (fully cooked)
● Chicken
● Fish
● Mutton (in moderation)
👉 Eggs are one of the best and cheapest protein sources

Yes, many patients can meet needs through food alone
❗ Supplements may be needed if:
● Appetite is poor
● You cannot eat enough food
● Doctor advises protein powder
Always consult your doctor before starting supplements.

Simple tips:
● Add paneer or dal to sabzi
● Eat curd with meals
● Add peanuts or chana as snacks
● Include eggs or milk daily
● Use dal + rice instead of plain rice

Breakfast: Milk + boiled eggs / paneer sandwich
Lunch: Dal + rice/roti + curd
Snack: Roasted chana / peanuts / milk
Dinner: Paneer/chicken/fish sabzi + roti

Dal is good, but dal + dairy or eggs/meat gives better protein quality.
👉 Combining foods improves protein absorption.

Yes, but in small amounts:
● Almonds, peanuts, seeds
● High in calories and fats
Good as snacks, not main protein source.

Not usually.
Protein is safe unless you have kidney disease.
Always follow your doctor’s advice if kidney function is abnormal.

● Soft foods (curd, dal, paneer bhurji)
● Small frequent meals
● Protein-rich liquids (milk, smoothies, soups)

Yes, it is very important for elderly patients to:
● Prevent muscle loss
● Improve strength and balance
Texture can be adjusted (soft, mashed foods).

🚫 Junk food
🚫 Sugary drinks
🚫 Excess fried foods
Protein should come from healthy, home-cooked food.

What are blood cancers?

Blood cancers are cancers that affect:
● Blood cells
● Bone marrow
● Lymphatic system
Common blood cancers include leukaemia, lymphoma, and multiple myeloma.

Learn more

Chemotherapy is a treatment that uses medicines to kill cancer cells or stop them from growing. In blood cancers, chemotherapy travels through the bloodstream and reaches cancer cells throughout the body.

Chemotherapy helps to:
● Kill abnormal blood cancer cells
● Control the disease
● Reduce symptoms
● Prepare patients for stem cell transplant (in some cases)

No.
Chemotherapy depends on:
● Type of blood cancer
● Stage of disease
● Age and general health
● Other medical conditions
Each patient receives a personalised treatment plan.

Chemotherapy may be given:
● Through a vein (IV drip)
● As tablets or capsules
● Through injections
● Sometimes into the spinal fluid (for specific conditions)

Chemotherapy itself is not painful.
You may feel:
● Mild discomfort during needle insertion
● Side effects later, which are manageable with medicines

Treatment duration varies:
● Days to months
● Given in cycles (treatment + rest period)
Your doctor will explain the exact schedule

Common side effects include:
● Tiredness
● Nausea or vomiting
● Hair loss
● Mouth sores
● Low blood counts
● Increased risk of infection
Not everyone gets all side effects.

Yes, immunity can become low temporarily.
Doctors monitor blood counts regularly and give:
● Antibiotics
● Growth factor injections
● Blood or platelet transfusions if needed

Hair loss depends on the medicines used.
Hair usually grows back after treatment

Yes, but:
● Eat clean, freshly cooked food
● Avoid raw or outside food if immunity is low
● Small, frequent meals are better

Many patients can continue light activities. Rest when tired and avoid crowded places when immunity is low.

Chemotherapy can:
● Cure some blood cancers
● Control disease in others
● Help achieve long-term remission

Yes.
Chemotherapy is given under strict medical supervision, and side effects are actively
managed.

Call your doctor immediately if you have:
● Fever >/= 99.5*F
● Severe vomiting or diarrhoea
● Bleeding or bruising
● Breathlessness
● Severe weakness

Some chemotherapy drugs may affect fertility.
Discuss fertility preservation options before starting treatment if relevant

Family can help by:
● Maintaining hygiene
● Supporting diet and medicines
● Providing emotional support
● Helping with hospital visits

Do all patients get side effects?

No.
Side effects vary from person to person.
Some patients have mild effects, some have none, and others may have more noticeable
symptoms.

● Chemotherapy affects fast-growing cells (cancer cells, but also hair, mouth,and blood cells).
● Immunotherapy activates the immune system, which may sometimes attack normal tissues.

CHEMOTHERAPY – COMMON SIDE EFFECTS

● Fatigue (tiredness)
● Nausea and vomiting
● Hair loss
● Mouth sores
● Low blood counts
● Increased risk of infections

Some chemotherapy drugs cause hair loss.
Hair usually grows back after treatment ends.

Fatigue is common.
Rest, proper nutrition, and light activity help improve energy.

Yes. Chemotherapy can lower white blood cells.
Doctors monitor blood counts and may give:
● Antibiotics
● Growth factor injections
● Hospital care if fever develops

Yes. Some patients may experience:
● Loss of appetite
● Nausea
● Diarrhoea or constipation
Medicines and diet changes usually help.

Most side effects are temporary and improve after treatment ends.

IMMUNOTHERAPY – COMMON SIDE EFFECTS

Immunotherapy helps the body’s immune system recognise and attack cancer cells.

Yes, but they are different from chemotherapy

● Fever or chills
● Fatigue
● Skin rash or itching
● Diarrhoea
● Body aches

Immunotherapy can make the immune system overactive, which may affect normal organs.

Rarely, immunotherapy can cause inflammation of:
● Lungs (breathlessness)
● Liver (jaundice)
● Gut (severe diarrhoea)
● Hormone glands (thyroid problems)
Early reporting makes treatment very effective.

COMPARISON: CHEMO vs IMMUNOTHERAPY

Chemotherapy Immunotherapy
Affects fast-growing cells Activates the immune system
Hair loss common Hair loss uncommon
Infection risk common Auto-immune reactions possible
Predictable side effects Side effects may appear late

Doctors may use:
● Anti-nausea medicines
● Antibiotics or steroids
● Temporary treatment breaks
● Supportive care and monitoring

Never stop treatment on your own.

During Chemotherapy & Neutropenia

Why is hygiene extra important for blood cancer patients?

Blood cancers affect the bone marrow and blood cells, which are vital for fighting infections.
Chemotherapy further lowers immunity, making even minor infections potentially serious.

Neutropenia means very low infection-fighting white blood cells.
During this phase:
● Infections may occur without obvious symptoms
● Fever may be the only warning sign

Very frequently:
● Before eating or drinking
● After using the toilet
● After touching IV lines, dressings, or catheters
● After coming from hospital visits

Use soap and water for at least 20 seconds.

Yes, daily bathing is recommended unless advised otherwise.
● Use lukewarm water
● Use mild, non-perfumed soap
● Gently pat skin dry
Avoid very hot water if platelet counts are low.

Blood cancer patients are prone to mouth sores and bleeding.
● Use a soft-bristled toothbrush
● Brush gently twice daily
● Avoid toothpicks and dental floss during low platelet counts
● Rinse your mouth after meals
● Use prescribed oral hygiene products like Hexidine Mouthwash and Lozenges (if prescribed by
your doctor)
Report mouth ulcers, pain, or bleeding immediately.

● Keep dressing clean, dry, and intact
● Do not touch the site unnecessarily
● Do not allow untrained people to handle it
● Inform staff if there is redness, pain, discharge, or fever
Refer to our information/ FAQs on Catheter Care

● Use an electric trimmer only
● Avoid blades, waxing, or threading
Cuts can bleed or get infected easily during low counts.

● Moisturise dry skin to prevent cracks
● Avoid cuts, burns, and insect bites
● Do not pop pimples or boils
● Avoid tattoos or piercings
Skin infections are common entry points for bacteria

● Keep nails short and clean
● Do not cut cuticles
● Avoid nail salons

● Clean, loose, cotton clothes
● Change daily
● Wash clothes separately if advised during neutropenia

Limited outdoor activity is allowed if you feel well.
Avoid:
● Crowded places
● People with cough, cold, and fever
● Construction or dusty areas
Wear a mask ( N95 preferred)

Yes, if visitors:
● Are completely healthy
● Wash your hands before contact
Avoid visitors with fever, cough, or recent infections

Yes, with precautions:
● Avoid cleaning litter boxes or pet waste
● Wash your hands after touching pets
● Avoid scratches or bites

● Use clean, well-maintained toilets
● Flush with lid closed (if possible)
● Wash your hands thoroughly after use

Yes, if:
● Hands are washed properly
● No cuts or wounds on hands
Avoid cooking during severe neutropenia if unwell

Urgent warning signs in blood cancer patients:
● Fever (even once)
● Chills or shivering
● Bleeding from gums, nose, urine, or stools
● Redness or pain around the IV line
● Severe mouth sores
● Burning during urination

Do not wait—early treatment saves lives.

What is a PICC catheter?

A PICC (Peripherally Inserted Central Catheter) is a long, thin tube placed in a vein in the
arm.
It allows doctors to give:
● Chemotherapy
● IV medicines
● Blood products
● Fluids
without repeated needle pricks.

A PICC line:
● Protects your veins
● Makes treatment easier and safer
● It is useful when treatment lasts many weeks or months

A PICC line can stay for weeks to months, as long as:
● It is working well
● There are no signs of infection or blockage

Insertion may cause mild discomfort.
After that, you should not feel pain at the site.
Pain, redness, or swelling is not normal and should be reported.

● Keep the dressing clean, dry, and covered
● Do not touch the site unnecessarily
● Never remove or change the dressing yourself unless trained

Yes, with precautions:
● Keep the PICC line completely dry
● Cover with a waterproof dressing during bathing
Avoid soaking the arm in water (no tubs or swimming)

Avoid:
● Heavy lifting with the PICC arm
● Vigorous exercises
● Pulling or tugging the line
Normal daily activities are allowed

Yes.
● Avoid sleeping on the PICC arm
● Ensure the line is not bent or kinked

● Dressing is usually changed once a week
● Or earlier if it becomes wet, loose, or dirty
Only trained staff should change it.

Contact your doctor immediately if you notice:
● Fever or chills
● Redness, swelling, or warmth at the site
● Pain or pus discharge
● Line slipping out

Contact your doctor immediately if you notice:
● Fever or chills
● Redness, swelling, or warmth at the site
● Pain or pus discharge
● Line slipping out

● Inform your nurse or doctor immediately
● Do not try to fix it yourself

No.
Do not allow:
● Blood pressure checks
● Injections
● Blood samples
from the PICC arm unless advised by your doctor.

Yes.
● Eat normally
● Travelling short distances is safe
● Avoid crowded places if immunity is low

Do not flush or force the line.
Contact your healthcare team.

The PICC line is removed:
● After treatment is complete
● If there is an infection, blockage, or damage
Removal is usually quick and painless

What is CAR-T cell therapy?

CAR-T cell therapy is an advanced cancer treatment where:
● A patient’s own immune cells (T cells) are collected
● They are genetically modified in a laboratory to attack cancer
● The modified cells are infused back into the patient
It is mainly used for certain blood cancers.

In India, CAR-T therapy is currently used for:
● Relapsed or refractory B-cell Acute Lymphoblastic Leukaemia (ALL)
● Certain B-cell lymphomas
Other indications are under clinical trials

Yes.
CAR-T therapy is now available at selected centres in India, including both:
● Indigenously developed CAR-T products
● Some international collaborations
However, availability is limited to specialised tertiary centres.

Eligibility depends on:
● Type of blood cancer
● Disease status (relapsed / refractory)
● Age and general health
● Organ function (heart, lungs, liver, kidneys)
Final eligibility is decided by a CAR-T multidisciplinary team.

No.
CAR-T is an immunotherapy, not chemotherapy.
However, short chemotherapy (lymphodepletion) is given before CAR-T infusion.

1. T-cell collection (apheresis)
2. Manufacturing of CAR-T cells (2–4 weeks in most cases)
3. Bridging therapy (if required)
4. CAR-T cell infusion
5. Close monitoring for side effects

● Cell collection to infusion: 3–6 weeks
● Hospital stay after infusion: 2–3 weeks
● Close follow-up for at least 1–3 months

Common side effects include:
● Fever
● Low blood pressure
● Low oxygen levels
● Weakness
These are usually related to Cytokine Release Syndrome (CRS).

CRS is an immune reaction caused by CAR-T cells attacking cancer.
Symptoms may include:
● High fever
● Chills
● Low BP
● Breathlessness
CRS is treatable if detected early.

Yes, some patients may develop neurological symptoms, such as:
● Confusion
● Headache
● Speech difficulty
● Drowsiness
These effects are usually temporary with proper care.

Yes, when done at trained centres with ICU backup.
Indian centres follow international safety protocols with local adaptations.

In India, CAR-T therapy is significantly less expensive than abroad, but still costly.
Costs may include:
● Cell manufacturing
● Hospitalisation and ICU care
● Medicines and supportive care
Some patients may access:
● Institutional support
● Government or trust-based funding
● Clinical trial options

Coverage varies:
● Some insurers partially cover costs
● Many policies still classify CAR-T as advanced or experimental
Always check with your hospital’s financial counselling team.

Not all patients need ICU care, but:
● ICU support must be readily available
● Some patients may need ICU monitoring for CRS or neurological effects

CAR-T therapy can lead to:
● Deep and long-lasting remissions in some patients, however,
● It is not a guaranteed cure
● Long-term follow-up is essential

Some patients may:
● Remain in remission without further therapy
● Need additional treatments later
Follow-up plans are individualised.

Yes.
CAR-T therapy can be given after relapse post-transplant, depending on the patient’s condition.

● Avoid infections
● Regular hospital follow-ups
● Caregiver support is essential
● Report fever or confusion immediately

Very important.
Caregivers help in:
● Monitoring symptoms
● Ensuring timely hospital visits
● Emotional and physical support

⭐ CAR-T is a powerful but complex therapy
⭐ Not all patients are eligible
⭐ Side effects are manageable at experienced centres
⭐ Financial and logistic planning is important